Characterization of GABA Receptors
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چکیده
منابع مشابه
Characterization of receptors for glutamate and GABA in retinal neurons.
Glutamate and gamma-aminobutyric acid (GABA) are major excitatory and inhibitory neurotransmitters in the vertebrate retina, "a genuine neural center" (Ramón y Cajal, 1964, Recollections of My Life, C.E. Horne (Translater) MIT Press, Cambridge, MA). Photoreceptors, generating visual signals, and bipolar cells, mediating signal transfer from photoreceptors to ganglion cells, both release glutama...
متن کاملGABA Receptors
Ian Martin is Professor of Pharmacology in the School of Life and Health Sciences at the University of Aston, Birmingham B4 7ET, UK. Susan Dunn is a Senior Lecturer in the Department of Pharmacology at the University of Bristol, University Walk, Bristol BS8 1TD, UK. They have common interests in GABAergic transmission in the central nervous system and their research is focused on the structure-...
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From an historical standpoint, the development of our understanding of basic mechanisms of the actions of gamma aminobutyric acid (GABA) and benzodiazepines began on separate paths. Classical pharmacology revealed similarity between the actions of GABA and benzodiazepines in the central nervous system. Furthermore, pharmacological experiments with selective agonists and antagonists indicated th...
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Gamma-aminobutyric acid (GABA) concentrations in seminal plasma and washed spermatozoa from normal donors were assessed by a sensitive radioreceptor assay, and were detectable in both fractions. Specific binding of [3H]-muscimol was shown to be dependent on protein concentration, temperature and incubation time. [3H]-muscimol specific binding to human sperm membranes was significantly inhibited...
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This article profiles ten examples of chemicals derived from herbal preparations that influence ionotropic receptors for the brain’s major inhibitory neurotransmitter g-aminobutyric acid (GABA). Many herbal medicines are used to influence brain function in order to treat anxiety, cognitive disorders, and insomnia. Such disorders are considered likely to involve GABA receptors, particularly iono...
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ژورنال
عنوان ژورنال: Current Protocols in Pharmacology
سال: 2013
ISSN: 1934-8282,1934-8290
DOI: 10.1002/0471141755.ph0107s63